As development progresses, the lens placode begins to deepen and invaginate.
2.
The optic visicle will then induce the ectoderm that thickens ( lens placode ) and further invaginates to a point that detaches from the ectoderm and forms a neurogenic placode by itself.
3.
During the invagination of the optic cup, the ectoderm begins to thicken and form the lens placode, which eventually separates from the ectoderm to form the lens vesicle at the open end of the optic cup.
4.
The lens placode is affected by the chordamesoderm making it to invaginate and forms the optic cup composed by an outer layer of neural retina and inner layer the pigmented retina that will unite and form the optic stalk.
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